We are in relentless pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a more healthy place. It was Charles Pfizer's initial vision, and it remains true today. Studies show what intuition tells us: that purpose-driven companies achieve more, are more creative, draw and keep the best professionals, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and represents the value we work to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.